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Download the fantastic book titled Drug Discovery in Cancer Epigenetics written by Gerda Egger, available in its entirety in both PDF and EPUB formats for online reading. This page includes a concise summary, a preview of the book cover, and detailed information about "Drug Discovery in Cancer Epigenetics", which was released on 19 November 2015. We suggest perusing the summary before initiating your download. This book is a top selection for enthusiasts of the Medical genre.

Summary of Drug Discovery in Cancer Epigenetics by Gerda Egger PDF

Drug Discovery in Cancer Epigenetics is a practical resource for scientists involved in the discovery, testing, and development of epigenetic cancer drugs. Epigenetic modifications can have significant implications for translational science as biomarkers for diagnosis, prognosis or therapy prediction. Most importantly, epigenetic modifications are reversible and epigenetic players are found mutated in different cancers; therefore, they provide attractive therapeutic targets. There has been great interest in developing and testing epigenetic drugs, which inhibit DNA methyltransferases, histone modifying enzymes or chromatin reader proteins. The first few drugs are already FDA approved and have made their way into clinical settings. This book provides a comprehensive summary of the epigenetic drugs currently available and aims to increase awareness in this area to foster more rapid translation of epigenetic drugs into the clinic. Highlights the potential of epigenetic alterations in cancer for drug development Covers the tools and methods for epigenetic drug discovery, preclinical and clinical testing, and clinical implications of epigenetic therapy Provides important information regarding putative epigenetic targets, epigenetic technologies, networks and consortia for epigenetic drug discovery and routes for translation


Detail About Drug Discovery in Cancer Epigenetics PDF

  • Author : Gerda Egger
  • Publisher : Academic Press
  • Genre : Medical
  • Total Pages : 498 pages
  • ISBN : 0128024925
  • PDF File Size : 13,6 Mb
  • Language : English
  • Rating : 4/5 from 21 reviews

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Drug Discovery in Cancer Epigenetics

Drug Discovery in Cancer Epigenetics
  • Publisher : Academic Press
  • File Size : 21,6 Mb
  • Release Date : 19 November 2015
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Drug Discovery in Cancer Epigenetics is a practical resource for scientists involved in the discovery, testing, and development of epigenetic cancer drugs. Epigenetic modifications can have significant implications for translational

Epigenetics for Drug Discovery

Epigenetics for Drug Discovery
  • Publisher : Royal Society of Chemistry
  • File Size : 54,7 Mb
  • Release Date : 20 November 2015
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Epigenetics is one of the fastest moving fields in drug discovery, with almost every large pharmaceutical company and a substantial number of biotechnology companies targeting epigenetic processes to treat diseases

Epigenetic Drug Discovery

Epigenetic Drug Discovery
  • Publisher : John Wiley & Sons
  • File Size : 55,5 Mb
  • Release Date : 26 November 2018
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This broad view of epigenetic approaches in drug discovery combines methods and strategies with individual targets, including new and largely unexplored ones such as sirtuins and methyl-lysine reader proteins. Presented

Epigenetic Drug Discovery

Epigenetic Drug Discovery
  • Publisher : John Wiley & Sons
  • File Size : 25,5 Mb
  • Release Date : 25 March 2019
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This broad view of epigenetic approaches in drug discovery combines methods and strategies with individual targets, including new and largely unexplored ones such as sirtuins and methyl-lysine reader proteins. Presented

Epi-Informatics

Epi-Informatics
  • Publisher : Academic Press
  • File Size : 46,6 Mb
  • Release Date : 24 February 2016
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Epi-Informatics: Discovery and Development of Small Molecule Epigenetic Drugs and Probes features multidisciplinary strategies with strong computational approaches that have led to the successful discovery and/or optimization of compounds

Epigenetic Approaches in Drug Discovery, Development and Treatment

Epigenetic Approaches in Drug Discovery, Development and Treatment
  • Publisher : Frontiers Media SA
  • File Size : 36,5 Mb
  • Release Date : 07 August 2020
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Establishment of a normal phenotype involves dynamic epigenetic regulation of gene expression that when affected contributes to human diseases. On a molecular level, epigenetic regulation is marked by specific covalent

Epigenetic Targets in Drug Discovery

Epigenetic Targets in Drug Discovery
  • Publisher : Wiley-VCH
  • File Size : 48,7 Mb
  • Release Date : 03 August 2009
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Fueled by the expertise of a team of international specialist authors, this first reference on the booming topic covers everything a drug researcher needs to know about targeting epigenetic mechanisms

Structural Biology in Drug Discovery

Structural Biology in Drug Discovery
  • Publisher : John Wiley & Sons
  • File Size : 55,9 Mb
  • Release Date : 09 January 2020
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With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biology in Drug Discovery: Methods, Techniques, and Practices describes principles, methods, applications,

Chemical Epigenetics

Chemical Epigenetics
  • Publisher : Springer Nature
  • File Size : 33,8 Mb
  • Release Date : 31 March 2020
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This book presents an authoritative review of the most significant findings about all the epigenetic targets (writers, readers, and erasers) and their implication in physiology and pathology. The book also

Epigenetic Cancer Therapy

Epigenetic Cancer Therapy
  • Publisher : Elsevier
  • File Size : 45,6 Mb
  • Release Date : 03 May 2023
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Epigenetic Cancer Therapy, Second Edition provides a comprehensive discussion of healthy and aberrant epigenetic biology, along with new discoveries to improve our understanding of cancer epigenetics and therapeutics. The book