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Download the fantastic book titled DNA Methylation and Complex Human Disease written by Michel Neidhart, available in its entirety in both PDF and EPUB formats for online reading. This page includes a concise summary, a preview of the book cover, and detailed information about "DNA Methylation and Complex Human Disease", which was released on 11 August 2015. We suggest perusing the summary before initiating your download. This book is a top selection for enthusiasts of the Science genre.

Summary of DNA Methylation and Complex Human Disease by Michel Neidhart PDF

DNA Methylation and Complex Human Disease reviews the possibilities of methyl-group-based epigenetic biomarkers of major diseases, tailored epigenetic therapies, and the future uses of high-throughput methylome technologies. This volume includes many pertinent advances in disease-bearing research, including obesity, type II diabetes, schizophrenia, and autoimmunity. DNA methylation is also discussed as a plasma and serum test for non-invasive screening, diagnostic and prognostic tests, as compared to biopsy-driven gene expression analysis, factors which have led to the use of DNA methylation as a potential tool for determining cancer risk, and diagnosis between benign and malignant disease. Therapies are at the heart of this volume and the possibilities of DNA demethylation. In cancer, unlike genetic mutations, DNA methylation and histone modifications are reversible and thus have shown great potential in the race for effective treatments. In addition, the authors present the importance of high-throughput methylome analysis, not only in cancer, but also in non-neoplastic diseases such as rheumatoid arthritis. Discusses breaking biomarker research in major disease families of current health concern and research interest, including obesity, type II diabetes, schizophrenia, and autoimmunity Summarizes advances not only relevant to cancer, but also in non-neoplastic disease, currently an emerging field Describes wholly new concepts, including the linking of metabolic pathways with epigenetics Provides translational researchers with the knowledge of both basic research and clinic applications of DNA methylation in human diseases


Detail About DNA Methylation and Complex Human Disease PDF

  • Author : Michel Neidhart
  • Publisher : Academic Press
  • Genre : Science
  • Total Pages : 552 pages
  • ISBN : 0127999205
  • PDF File Size : 47,6 Mb
  • Language : English
  • Rating : 4/5 from 21 reviews

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DNA Methylation and Complex Human Disease

DNA Methylation and Complex Human Disease
  • Publisher : Academic Press
  • File Size : 42,8 Mb
  • Release Date : 11 August 2015
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DNA Methylation and Complex Human Disease reviews the possibilities of methyl-group-based epigenetic biomarkers of major diseases, tailored epigenetic therapies, and the future uses of high-throughput methylome technologies. This volume includes

Human Epigenetics: How Science Works

Human Epigenetics: How Science Works
  • Publisher : Springer Nature
  • File Size : 40,9 Mb
  • Release Date : 24 September 2019
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The view “It’s all in our genes and we cannot change it” developed in the past 150 years since Gregor Mendel’s experiments with flowering pea plants. However, there is

Computational Epigenetics and Diseases

Computational Epigenetics and Diseases
  • Publisher : Academic Press
  • File Size : 37,7 Mb
  • Release Date : 06 February 2019
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Computational Epigenetics and Diseases, written by leading scientists in this evolving field, provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases. In particular, the major computational tools,

Epigenetics in Human Disease

Epigenetics in Human Disease
  • Publisher : Academic Press
  • File Size : 22,5 Mb
  • Release Date : 26 July 2012
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Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene

Environmental Epigenomics in Health and Disease

Environmental Epigenomics in Health and Disease
  • Publisher : Springer Science & Business Media
  • File Size : 52,6 Mb
  • Release Date : 13 May 2013
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There are now compelling human epidemiological and animal experimental data that indicate the risk of developing adult-onset complex diseases and neurological disorders are influenced by persistent epigenetic adaptations in response

Network Medicine

Network Medicine
  • Publisher : Harvard University Press
  • File Size : 41,8 Mb
  • Release Date : 01 February 2017
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Big data, genomics, and quantitative approaches to network-based analysis are combining to advance the frontiers of medicine as never before. With contributions from leading experts, Network Medicine introduces this rapidly

DNA Methylation: Development, Genetic Disease and Cancer

DNA Methylation: Development, Genetic Disease and Cancer
  • Publisher : Springer
  • File Size : 53,6 Mb
  • Release Date : 16 November 2010
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It has become apparent that the genomes of many organisms are characterized by unique patterns of DNA methylation which can differ from genome segment to genome segment and cell type

Epigenetics and Complex Traits

Epigenetics and Complex Traits
  • Publisher : Springer Science & Business Media
  • File Size : 39,8 Mb
  • Release Date : 17 September 2013
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This book will provide an overview of basic epigenetic phenomena; interaction between epigenetic and genetic factors; and the influence of epigenetic factors on inheritance. Epigenetic states may contribute to the

Methylation

Methylation
  • Publisher : Inst za onkologiju i radiol
  • File Size : 37,7 Mb
  • Release Date : 28 November 2012
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Alterations in the normal DNA methylation processes are known to have major consequences for embryonic development and are associated with congenital defects, autoimmunity, aging and malignant transformation. The main purpose